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TREATMENTS ARTICLE: For some people with mild hepatitis C, the only treatment
needed may be eating a nutritious diet, avoiding alcohol, exercising regularly, and visiting a
doctor regularly to monitor the disease. But for others with hepatitis C, drug therapy may be
appropriate. The FDA has approved two different treatment regimens for chronic hepatitis C:
monotherapy (using a single drug, interferon) and combination therapy (using two drugs, interferon
and ribavirin). Interferon, which is injected into the bloodstream, works by bolstering the immune
response to HCV. Ribavirin, which is taken orally, may work by preventing the virus from
reproducing (viral replication). Taken alone, ribavirin does not effectively suppress levels of the
virus in the bloodstream. But studies have shown that the interferon and ribavirin combination,
approved in 1998, is more effective than interferon alone. The FDA has approved one ribavirin
product and four interferon products to treat HCV. Rebetol, the ribavirin product, is made by
Schering-Plough Corp. of Kenilworth, N. J. The interferon products are: Intron A and PEG-Intron
(made by Schering-Plough), Roferon-A (Hoffmann-La Roche Inc. , Nutley, NJ), and Infergen (Amgen
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ribavirin. The goal of treatment is sustained response--meaning that the virus is not measurable in
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response to HCV. Ribavirin, which is taken orally, may work by preventing the virus from
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virus in the bloodstream. But studies have shown that the interferon and ribavirin combination,
approved in 1998, is more effective than interferon alone.The FDA has approved one ribavirin
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response--meaning that the virus is not measurable in the blood after drug therapy is completed.
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virus from reproducing (viral replication). Taken alone, ribavirin does not effectively suppress
levels of the virus in the bloodstream. But studies have shown that the interferon and ribavirin
combination, approved in 1998, is more effective than interferon alone.The FDA has approved one
ribavirin product and four interferon products to treat HCV. Rebetol, the ribavirin product, is
made by Schering-Plough Corp. of Kenilworth, N.J. The interferon products are: Intron A and
PEG-Intron (made by Schering-Plough), Roferon-A (Hoffmann-La Roche Inc., Nutley, NJ), and Infergen
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TREATMENTS ARTICLE: For some people with mild hepatitis C, the only treatment needed may be
eating a nutritious diet, avoiding alcohol, exercising regularly, and visiting a doctor regularly
to monitor the disease.
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injected once a week. Only Intron A and PEG-Intron are approved for use in combination with
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