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Non-alcoholic steatohepatitis (NASH) is a type of hepatitis which resembles alcoholic hepatitis on liver biopsy (fat droplets, inflammatory cells, but usually no Mallory's hyalin) but occurs in patients who have no known history of alcohol abuse features. non alcoholic fatty liver disease NASH is more common in women and the most common cause is obesity or the metabolic syndrome features. non alcoholic fatty liver disease A related but less serious condition is called "fatty liver" (steatosis hepatis), which occurs in up to 80% of all clinically obese people features. non alcoholic fatty liver disease A liver biopsy for fatty liver shows fat droplets throughout the liver, but no signs of inflammation or Mallory's hyalin features. non alcoholic fatty liver diseaseThe diagnosis depends on history, physical exam, blood tests, radiological imaging and sometimes a liver biopsy features. non alcoholic fatty liver disease The initial evaluation to identify the presence of fatty infiltration of the liver is radiologic imaging including ultrasound, computed tomographic imaging, or magnetic resonance imaging features. non alcoholic fatty liver disease However, radiologic imaging cannot readily identify inflammation in the liver features. non alcoholic fatty liver disease Therefore, the differentiation between steatosis and NASH often requires a liver biopsy features. non alcoholic fatty liver disease It can also be difficult to distinguish NASH from alcoholic hepatitis when the patient has a history of alcohol consumption features. non alcoholic fatty liver disease Sometimes in such cases a trial of abstinence from alcohol along with follow -up blood tests and a repeat liver biopsy are required features. non alcoholic fatty liver diseaseNASH is becoming recognized as the most important cause of liver disease second only to Hepatitis C in numbers of patients going on to cirrhosis features. non alcoholic fatty liver disease

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Non-alcoholic steatohepatitis (NASH) is a type of hepatitis which resembles alcoholic hepatitis on liver biopsy (fat droplets, inflammatory cells, but usually no Mallory's hyalin) but occurs in patients who have no known history of alcohol abuse aspiration NASH is more common in women and the most common cause is obesity or the metabolic syndrome aspiration A related but less serious condition is called "fatty liver" (steatosis hepatis), which occurs in up to 80% of all clinically obese people. A liver biopsy for fatty liver shows fat droplets throughout the liver, but no signs of inflammation or Mallory's hyalin.The diagnosis depends on history, physical exam, blood tests, radiological imaging and sometimes a liver biopsy. The initial evaluation to identify the presence of fatty infiltration of the liver is radiologic imaging including ultrasound, computed tomographic imaging, or magnetic resonance imaging. However, radiologic imaging cannot readily identify inflammation in the liver. Therefore, the differentiation between steatosis and NASH often requires a liver biopsy. It can also be difficult to distinguish NASH from alcoholic hepatitis when the patient has a history of alcohol consumption. Sometimes in such cases a trial of abstinence from alcohol along with follow -up blood tests and a repeat liver biopsy are required.NASH is becoming recognized as the most important cause of liver disease second only to Hepatitis C in numbers of patients going on to cirrhosis.

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